Exceptional Nuclease Resistance of Paranemic Crossover (PX) DNA and Crossover-Dependent Biostability of DNA Motifs

Arun Richard Chandrasekaran, Javier Vilcapoma, Paromita Dey, Siu Wah Wong-Deyrup, Bijan K. Dey, Ken Halvorsen

J. Am. Chem. Soc. · March 25, 2020

Bacterial group II intron genomic neighborhoods reflect survival strategies: hiding and hijacking

Waldern J, Schiraldi NJ, Belfort M, Novikova O.

Mol Biol Evol · March 05, 2020

Locally acting transcription factors regulate p53-dependent cis-regulatory element activity

Allison N Catizone, Gizem Karsli Uzunbas, Petra Celadova, Sylvia Kuang, Daniel Bose, Morgan A Sammons

Nucleic Acids Research · March 05, 2020

How to Perform miRacles: A Step-by-Step microRNA Detection Protocol Using DNA Nanoswitches.

Chandrasekaran AR, Dey BK, Halvorsen K.

Curr Protoc Mol Biol. · March 01, 2020

Drug Screen Tugs at Common Thread for Repeat Disorders.

Reddy K, Cleary JD, Berglund JA.

Trends Pharmacol Sci. · February 01, 2020

The potential of engineered eukaryotic RNA-binding proteins as molecular tools and therapeutics

Shotwell CR, Cleary JD, Berglund JA.

Wiley Interdiscip Rev RNA. · January 11, 2020

Gli3 Regulates Vomeronasal Neurogenesis, Olfactory Ensheathing Cell Formation, and GnRH-1 Neuronal Migration

Taroc EZM, Naik AS, Lin JM, Peterson NB, Keefe DL Jr, Genis E, Fuchs G, Balasubramanian R, Forni PE.

J Neurosci. · January 08, 2020

Regional Differences following Partial Salivary Gland Resection

O'Keefe KJ, DeSantis KA, Altrieth AL, Nelson DA, Taroc EZM, Stabell AR, Pham MT, Larsen M.

J Dent Res. · January 01, 2020

Sequential Regulation of Maternal mRNAs through a Conserved cis-Acting Element in Their 3′ UTRs

PoojaFlora12Siu WahWong-Deyrup1, Elliot, ToddMartin1, RyanJ.Palumbo13, MohamadNasrallah14, AndrewOligney15, PatrickBlatt1, DhruvPatel16, GabrieleFuchs1, PrashanthRangan17

Cell Reports · December 26, 2019

Rationally Engineered Nucleic Acid Architectures for Biosensing Applications.

Xiao M, Lai W, Man T, Chang B, Li L, Chandrasekaran AR, Pei H.

Chem Rev. · November 27, 2019

DNA nanotechnology approaches for microRNA detection and diagnosis.

Chandrasekaran AR, Punnoose JA, Zhou L, Dey P, Dey BK, Halvorsen K.

Nucleic Acids Res. · November 18, 2019

Epitranscriptomic marks: Emerging modulators of RNA virus gene expression

Netzband R, Pager CT.

Wiley Interdiscip Rev RNA. · November 06, 2019

Epitranscriptomic systems regulate the translation of reactive oxygen species detoxifying and disease linked selenoproteins

Leonardi A, Evke S, Lee M, Melendez JA, Begley TJ

Free Radic Biol Med · November 01, 2019

A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels

Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA.

Proc Natl Acad Sci U S A · October 15, 2019

Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing

Green CM, Li Z, Smith AD, Novikova O, Bacot-Davis VR, Gao F, Hu S, Banavali NK, Thiele DJ, Li H, Belfort M

PLoS Biol · October 10, 2019

Molecular mechanism of poliovirus Sabin vaccine strain attenuation

Avanzino BC, Jue H, Miller CM, Cheung E, Fuchs G, Fraser CS

The Journal of Biological Chemistry · October 05, 2019

Detecting miRNAs Using DNA Nanoswitches.

Chandrasekaran AR.

Trends Biochem Sci. · September 01, 2019

Bio-orthogonal chemistry-based method for fluorescent labelling of ribosomal RNA in live mammalian cells

Wu K, He M, Khan I, Asare Okai PN, Lin Q, Fuchs G, Royzen M.

Chem Commun (Camb). · August 27, 2019

HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting

Mubaid S, Ma JF, Omer A, Ashour K, Lian XJ, Sanchez BJ, Robinson S, Cammas A, Dormoy-Raclet V, Di Marco S, Chittur SV, Tenenbaum SA, Gallouzi IE.

Proc Natl Acad Sci U S A. · August 27, 2019

Surface Enhanced Raman Spectroscopy for Single Molecule Protein Detection

Almehmadi LM, Curley SM, Tokranova NA, Tenenbaum SA, Lednev IK.

Sci Rep. · August 26, 2019

Click and photo-release dual-functional nucleic acid nanostructures

Valsangkar VA, Chandrasekaran AR, Zhuo L, Mao S, Lee GW, Kizer M, Wang X, Halvorsen K, Sheng J.

Chem Commun (Camb). · August 21, 2019

Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules.

Reddy K, Jenquin JR, Cleary JD, Berglund JA.

Int J Mol Sci. · August 17, 2019

Combination Treatment of Erythromycin and Furamidine Provides Additive and Synergistic Rescue of Mis-Splicing in Myotonic Dystrophy Type 1 Models

Jenquin JR, Yang H, Huigens RW 3rd, Nakamori M, Berglund JA.

ACS Pharmacol Transl Sci. · August 09, 2019

Mechanism of Single-Stranded DNA Activation of Recombinase Intein Splicing

Lennon CW, Stanger MJ, Belfort M

Biochemistry · August 06, 2019

Cisplatin protects mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein

Li Z, Fu B, Green CM, Liu B, Zhang J, Lang Y, Chaturvedi S, Belfort M, Liao G, Li H.

Emerg Microbes Infect. · August 01, 2019

Modification of messenger RNA by 2'-O-methylation regulates gene expression in vivo

Elliott BA, Ho HT, Ranganathan SV, Vangaveti S, Ilkayeva O, Abou Assi H, Choi AK, Agris PF, Holley CL.

Nat Commun. · July 30, 2019

Identification and Quantification of Modified Nucleosides in Saccharomyces cerevisiae mRNAs

Tardu M, Jones JD, Kennedy RT, Lin Q, Koutmou KS.

ACS Chem Biol. · July 19, 2019

Repeat-associated RNA structure and aberrant splicing.

Hale MA, Johnson NE, Berglund JA.

Biochim Biophys Acta Gene Regul Mech. · July 16, 2019

A Molecular Hero Suit for In Vitro and In Vivo DNA Nanostructures

Kizer ME, Linhardt RJ, Chandrasekaran AR, Wang X.

Small. · June 15, 2019

Integration of a photocleavable element into DNA nanoswitches

Chandrasekaran AR, Abraham Punnoose J, Valsangkar V, Sheng J, Halvorsen K.

Chem Commun (Camb). · June 11, 2019

Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression

Bonenfant G, Williams N, Netzband R, Schwarz MC, Evans MJ, Pager CT.

J Virol. · May 29, 2019

CoSIMS: An Optimized Trajectory-Based Collision Simulator for Ion Mobility Spectrometry

Myers CA, D'Esposito RJ, Fabris D, Ranganathan SV, Chen AA.

J Phys Chem B. · May 23, 2019

pH-Operated Triplex DNA Device on MoS2 Nanosheets

Ji W, Li D, Lai W, Yao X, Alam MF, Zhang W, Pei H, Li L, Chandrasekaran AR.

Langmuir · April 09, 2019

Structure of an engineered intein reveals thiazoline ring and provides mechanistic insight

Pearson CS, Nemati R, Liu B, Zhang J, Scalabrin M, Li Z, Li H, Fabris D, Belfort M, Belfort G.

Biotechnol Bioeng. · April 01, 2019

Cellular microRNA detection with miRacles: microRNA- activated conditional looping of engineered switches

Chandrasekaran AR, MacIsaac M, Dey P, Levchenko O, Zhou L, Andres M, Dey BK, Halvorsen K.

Sci Adv. · March 13, 2019

General Recognition of U-G, U-A, and C-G Pairs by Double-Stranded RNA-Binding PNAs Incorporated with an Artificial Nucleobase

Ong AAL, Toh DK, Patil KM, Meng Z, Yuan Z, Krishna MS, Devi G, Haruehanroengra P, Lu Y, Xia K, Okamura K, Sheng J, Chen G.

Biochemistry · March 12, 2019

Controlled disassembly of a DNA tetrahedron using strand displacement

Chandrasekaran AR, Halvorsen K.

Nanoscale Adv. · March 01, 2019

Vector Competence of Aedes caspius and Ae. albopictus mosquitoes for Zika virus, Spain

Gutiérrez-López R, Bialosuknia SM, Ciota AT, Montalvo T, Martínez-de la Puente J, Gangoso L, Figuerola J, Kramer LD

Emerging Infectious Diseases · February 25, 2019

tRNA modification and cancer: potential for therapeutic prevention and intervention

Endres L, Fasullo M, Rose R.

Furture Medicinal Chemistry · February 12, 2019

E3 ubiquitin ligase Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling

Cho JJ, Mansouri S, Drashansky TT, Helm EY, Zuniga AN, Xu Z, Parthasarathy U, Lorentsen KJ, Uddin MN, Duong DM, Edelmann MJ, Gehring T, Krappmann D, Califano D, Li HM, Wang RL, Cho JY, Jin L, Zhou L, Avram D

Nature Communications · February 11, 2019

Sequential Regulation of Maternal mRNAs through a Conserved cis-Acting Element in Their 3' UTRs

Flora P, Wong-Deyrup SW, Martin ET, Palumbo RJ, Nasrallah M, Oligney A, Blatt P, Patel D, Fuchs G, Rangan P

Cell Reports · December 26, 2018

Blood-treatment of Lyme borreliae demonstrates the mechanism of CspZ-mediated complement evasion to promote systemic infection in vertebrate hosts

Marcinkiewicz AL, Dupuis AP 2nd, Zamba-Campero M, Nowak N, Kraiczy P, Ram S, Kramer LD, Lin YP

Cell Microbiology · December 20, 2018

Bio-Orthogonal Chemistry and Reloadable Biomaterial Enable Local Activation of Antibiotic Prodrugs and Enhance Treatments against Staphylococcus aureus Infections

Magdalena Czuban, Sangeetha Srinivasan, Nathan A. Yee, Edgar Agustin, Anna Koliszak, Ethan Miller, Irfan Khan∥, Ilenis Quinones∥, Hasina Noory∥, Christopher Motola∥, Rudolf Volkmer, Mariagrazia Di Luca, Andrej Trampuz, Maksim Royzen, and Jose M. Mejia Oneto

ACS Central Science · December 12, 2018

Tip60 complex promotes expression of a differentiation factor to regulate germline differentiation in female Drosophila

Alicia McCarthy, Aron Deiulio, Elliot Todd Martin, Maitreyi Upadhyay, Prashanth Rangan, Denise Montell

Molecular Biology of The Cell · November 26, 2018

Structure of an Engineered Intein Reveals Thiazoline Ring and Provides Mechanistic Insight as a Splicing Switch

Pearson SC, Nemati R, Liu B, Zhang J, Scalabrin M, Li Z, Li HM, Fabris D, Belfort M, Belfort G

Biotechnology and Bioengineering · November 18, 2018

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment.

Worley BL1, Kim YS1, Mardini J1, Zaman R1, Leon KE2, Vallur PG1, Nduwumwami A1, Warrick JI3, Timmins PF4, Kesterson JP5, Phaëton R6, Lee NY7, Walter V8, Endres L9, Mythreye K10, Aird KM2, Hempel N11

Redox Biology · November 17, 2018

Mycobacterial DnaB helicase intein as oxidative stress sensor

Kelley DS, Lennon CW, Li Z, Miller MR, Banavali N, Li HM, Belfort M

Nature Communications · October 19, 2018

DNA nanocarriers: Programmed to deliver

BR Madhanagopal, S Zhang, E Demirel, H Wady and AR Chandrasekaran

Trends in Biomedical Sciences · October 18, 2018

Furamidine Rescues Myotonic Dystrophy Type I Associated Mis-Splicing through Multiple Mechanisms.

Jenquin JR, Coonrod LA, Silverglate QA, Pellitier NA, Hale MA, Xia G, Nakamori M, Berglund JA.

ACS Chem Biol. · September 21, 2018

MrpJ Directly Regulates Proteus mirabilis Virulence Factors, Including Fimbriae and Type VI Secretion, during Urinary Tract Infection

Debnath, I., Stringer, A. M., Smith, S. N., Bae, E., Mobley, H. L. T., Wade, J. T. and Pearson, M. M.

Infection and Immunity · September 21, 2018

Extensive recoding of dengue virus type 2 specifically educes replication in primate cells without gain-of-function in Aedes aegypti mosquitoes

Stauft CB, Shen SH, Song Y, Gorbatsevych O, Asare E, Futcher B, Mueller S, Payne A, Brecher M, Kramer L, Wimmer E

PloS one · September 07, 2018

An engineered RNA binding protein with improved splicing regulation.

Hale MA, Richardson JI, Day RC, McConnell OL, Arboleda J, Wang ET, Berglund JA.

Nucleic Acids Res. · April 06, 2018

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